HEVEBLUE Salmon Caring Centella Ampoule is a lightweight salmon PDRN serum with centella for sensitive, irritated skin prone to redness. Its main ingredient is centella leaf water, paired with salmon PDRN and hyaluronic acid. Fragrance-free; use morning and evening after toner.
Product detailed description
PDRN serum with centella · Soothing care for sensitive skin
Your skin stings after cleansing, your cheeks and the area around your nose redden easily, and some serums seem to unsettle it rather than calm it. HEVEBLUE Salmon Caring Centella Ampoule is a lightweight salmon PDRN serum with centella for sensitive skin: its main ingredient is centella asiatica leaf water, supported by several humectants including hyaluronic acid, with PDRN from salmon DNA as an additional conditioning ingredient. Compared with a simple centella-only ampoule, it has a more complex formula with salmon-derived ingredients.
Use it morning and evening after toner, before moisturiser. At VIONE, we recommend it as one lightweight, fragrance-free hydrating layer when you want to keep a sensitive-skin routine simple.
- Type: soothing, hydrating ampoule (serum), 30 ml, with dropper
- Suitable for: sensitive skin prone to redness, irritated or dehydrated skin
- Key ingredients: centella asiatica leaf water, PDRN (sodium DNA), salmon egg extract, madecassoside, hyaluronic acid
- Fragrance-free · Serum step, morning and evening
Routine step
HEVEBLUE Salmon Caring Centella Ampoule is the Serum step: after toner, before moisturiser. Finish with SPF in the morning.
Who the HEVEBLUE PDRN centella serum is for
- Your skin is easily irritated and prone to redness, for example after cleansing, in the wind or when you come in from the cold into a heated room.
- Your skin needs gentler care between active treatments: you use retinoids, acids or exfoliants and want a layer for the days in between that doesn't add more actives.
- Your skin feels tight and dehydrated, but rich creams don't suit you and you are looking for lightweight hydration.
- You avoid fragrance and essential oils because your skin reacts to them.
- You are curious about PDRN (salmon DNA) and want to try it in a gentle, soothing formula without strong exfoliating actives.
When to choose something else: you want vegan skincare (the ampoule contains salmon-derived ingredients), you are allergic to fish or wheat protein, or you need to target dark spots or acne specifically. Serums with other active ingredients are a better fit for that.
Texture and skin feel
- Watery gel texture that absorbs quickly.
- A light layer under moisturiser: retailers describe it as fast-absorbing and non-sticky, so it layers well under cream.
- Fragrance-free: contains no perfume and no essential oils.
Tip: the brand also suggests a short compress. Put a few drops on a cotton pad soaked in toner and hold it on the area that needs care for 30 seconds to 1 minute. For sensitive or irritated skin, start with regular application first.
Key ingredients: centella, salmon DNA (PDRN) and salmon roe
- Centella asiatica leaf water: the main ingredient in the formula; 847,474 ppm (about 85%) according to the brand. Centella is one of the most widely used soothing botanicals in Korean skincare. It may help ease the feeling of irritation and is a popular choice for sensitive skin with a weakened barrier.
- PDRN (listed as Sodium DNA): the brand states 10,000 ppm PDRN. It is polydeoxyribonucleotide, fragments of DNA taken from salmonid fish, in this ampoule from salmon according to the brand. In aesthetic medicine it is mainly used as an injectable. In skincare it is a skin-conditioning ingredient whose effects when applied topically are still being studied. The ampoule's hydrating properties come from the overall formula, including glycerin, betaine and hyaluronic acid.
- Salmon egg extract, 1,500 ppm according to the brand: the conditioning ingredient that gives the ampoule its name.
- Madecassoside and purslane (Portulaca oleracea): madecassoside is one of the main compounds in centella, and purslane is used in skincare for its soothing properties. Together they target red, irritated skin.
- Three forms of hyaluronic acid and betaine: they bind water in the skin and help ease the feeling of tightness without weighing it down.
- Avocado, cocoa and quinoa: plant extracts in smaller amounts that round out the formula.
How to use HEVEBLUE Salmon Caring Centella Ampoule
- 1. Cleanse: a gentle cleanser; in the evening, if you wear SPF or makeup, start with a cleansing oil.
- 2. Toner: dampen your skin with toner so the ampoule spreads more easily.
- 3. Ampoule: apply a small amount to the whole face, spread gently and allow it to absorb.
- 4. Moisturiser: seal in the hydration with a cream.
- 5. SPF in the morning: as the last step.
- With active skincare: on evenings with a retinoid or acid you can use it as a soothing layer. Follow the instructions of the active product for the order.
FAQ
Frequently asked questions about HEVEBLUE Salmon Caring Centella Ampoule
What is PDRN and what can I expect from it in this ampoule?
PDRN (polydeoxyribonucleotide, listed in the INCI as Sodium DNA) consists of DNA fragments taken from salmonid fish, in this ampoule from salmon according to the brand. In Korea it became known mainly through aesthetic medicine, where it is injected. In skincare it is a conditioning ingredient whose effects when applied topically are still being studied. The ampoule is designed to hydrate and care for sensitive skin; that comes from the overall formula, with PDRN as an additional ingredient. Don't expect the effect of an in-clinic treatment. Individual responses and the resulting skin feel may vary.
Is the ampoule suitable for sensitive skin or skin prone to redness?
Yes, it is designed for sensitive skin. It contains no fragrance, essential oils or ethanol. The brand cites an irritation test by the Korea Institute of Dermatological Sciences with an index of 0.00. This does not rule out individual reactions, so try it on a small area first. If you have diagnosed rosacea or eczema, introduce new products one at a time and ideally after talking to your dermatologist.
How soon will I see a difference?
Your skin may feel more hydrated after application, depending on its condition and individual response. Improvements in the appearance of redness cannot be guaranteed within a specific timeframe: it depends on what is causing the irritation and how your skin responds to the ampoule. If it suits you, use it regularly morning and evening.
Is the ampoule vegan?
No. PDRN (sodium DNA) and the roe extract come from salmon, so the ampoule is not vegan. The brand describes it as cruelty-free. If you are looking for skincare without animal-derived ingredients, choose a product in serums & ampoules where the brand states this explicitly.
I have a fish or wheat allergy. Can I use the ampoule?
The ampoule contains salmon-derived ingredients and hydrolysed wheat protein (Hydrolyzed Wheat Protein). If you have a confirmed fish or wheat allergy, ask your doctor before using it and show them the ingredient list below.
How is it different from SKIN1004 Madagascar Centella Ampoule?
Both are lightweight centella ampoules for sensitive skin. SKIN1004 Madagascar Centella Ampoule is built almost entirely on centella extract. HEVEBLUE has a more complex hydrating formula with PDRN, salmon egg extract and several moisturising ingredients. Choose SKIN1004 if you prefer a simpler centella-focused formula.
Who is the ampoule not for, and when should I choose another product?
Skip the ampoule if you want vegan skincare or need to target dark spots, acne or deeper wrinkles. This is primarily a hydrating and soothing ampoule, not a targeted exfoliating or pigmentation serum. For pigmentation and wrinkles, serums with other active ingredients are a better fit. If your skin mainly needs stronger barrier care, prioritise a cream such as PURITO Mighty Bamboo Panthenol Cream.
Can I combine the ampoule with retinol, vitamin C or acids?
The ampoule itself contains no retinoids or exfoliating acids. Depending on tolerance, it may fit into a routine with active skincare. Introduce new products one at a time and follow the active product's instructions for order and frequency. If your skin starts burning, becomes significantly red or begins to peel, stop using newly introduced products and return to a simple, well-tolerated routine. Consult a dermatologist if symptoms persist.
Can I use the ampoule during pregnancy?
According to its ingredient list, the ampoule contains no retinoids. We still recommend discussing any new skincare with your doctor during pregnancy and breastfeeding and showing them the ingredient list below.
What to pair the HEVEBLUE ampoule with
- ANUA Heartleaf 77 Soothing Toner: a soothing toner before the ampoule; it dampens the skin so the ampoule spreads more easily.
- PURITO Mighty Bamboo Panthenol Cream: a panthenol cream that seals in hydration after the ampoule and supports the barrier.
- AXIS-Y Complete No-Stress Physical Sunscreen SPF 50+: a zinc-based sunscreen as the last step in the morning. Sun is a common trigger for redness.
Practical tip: when your skin is very irritated, a gentle cleanser, the HEVEBLUE ampoule, a moisturiser and SPF in the morning are enough. You can leave out toner for a few days and bring it back once your skin has calmed down.
What the brand says
According to HEVEBLUE, the ampoule contains 847,474 ppm centella asiatica leaf water, 10,000 ppm PDRN and 1,500 ppm salmon egg extract. The brand reports an irritation index of 0.00 in a test by the Korea Institute of Dermatological Sciences. According to the brand, it is free of fragrance, essential oils, ethanol, silicone oils and artificial colourants, and the brand describes it as cruelty-free. Use within 12 months of opening. The stated concentrations and test results are based on the manufacturer's declarations. Individual skin tolerance may vary.
INCI / ingredients
Centella Asiatica Leaf Water, Butylene Glycol, Water, Propanediol, 1,2-Hexanediol, Glycerin, Sodium DNA, Salmon Egg Extract, Madecassoside, Portulaca Oleracea Water, Persea Gratissima (Avocado) Fruit Extract, Maltodextrin, Hyaluronic Acid, Hydrolyzed Hyaluronic Acid, Theobroma Cacao (Cocoa) Extract, Chenopodium Quinoa Seed Extract, Hydrolyzed Wheat Protein, Betaine, Dextrin, Sodium Hyaluronate, Carbomer, Ethylhexylglycerin, Ammonium Acryloyldimethyltaurate/VP Copolymer, Tromethamine, Disodium EDTA
The ingredient list may vary slightly between batches. Always check the product packaging for the final version.
| Category: | Serums & Ampoules |
|---|---|
| EAN: | 8809653247143 |
| Routine step: | Serum |
| Skin type: | normal, dry, combination, sensitive |
| Targets: | hydration, soothing |
| Active ingredient: | centella, hyaluronic acid, PDRN |
| Features: | fragrance-free |
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HEVEBLUE: Korean centella and PDRN skincare for sensitive skin
HEVEBLUE is a South Korean skincare brand for sensitive skin, run by the Seoul-based company Cosmento Korea. It is known mainly for its Salmon Caring Centella line, which pairs centella asiatica with PDRN, DNA fragments that the brand sources from salmon. According to Korean press reports, HEVEBLUE has also been sold at Sephora in the US since September 2026.
If your skin feels tight after cleansing, flushes easily and often does not tolerate more intensive serums, HEVEBLUE is worth considering. Salmon Caring Centella Ampoule combines centella-based water with a lightweight hydrating texture, while PDRN plays a supporting skincare role.
Why we chose HEVEBLUE
PDRN comes with a lot of promises in Korean skincare right now. We selected HEVEBLUE primarily for its focus on sensitive skin. Salmon Caring Centella Ampoule is built on centella asiatica leaf water, which the brand declares at 847,474 ppm, or roughly 85% of the formula. PDRN plays a supporting role. For skin that reacts easily to intensive skincare, the ampoule offers a clear approach: a lightweight hydrating step centred on centella, with PDRN as a supporting rather than the main selling point.
The effects of PDRN applied to the skin are still being researched. That is why we present it as an interesting extra, not as the main reason to buy.
Who HEVEBLUE is for
- Your skin is sensitive and prone to redness, reacting to wind, cold or heated rooms.
- Your skin feels dehydrated after cleansing and you want a light, fragrance-free layer under your moisturiser.
- You want to try PDRN (salmon DNA) in an ampoule designed for sensitive skin rather than a strong active serum.
If your main concern is dark spots or wrinkles, targeted care from Brightening & pigmentation or Mature skin 35+ will suit you better.
HEVEBLUE at VIONE
- HEVEBLUE Salmon Caring Centella Ampoule: a lightweight watery-gel serum (ampoule) with centella, PDRN and hyaluronic acid, fragrance-free. Use morning and evening after toner, before moisturiser.
HEVEBLUE: frequently asked questions
Is HEVEBLUE a Korean brand?
Yes. HEVEBLUE is a South Korean skincare brand for sensitive skin, run by Cosmento Korea, a company based in Seoul.
What does salmon DNA mean in skincare?
In skincare, salmon DNA refers to PDRN (polydeoxyribonucleotide), listed in the INCI as Sodium DNA. These are DNA fragments obtained from salmonid fish. It is used as a conditioning ingredient; its effects when applied to the skin are still being researched.
Which skin type is HEVEBLUE suitable for?
The ampoule is designed with sensitive and dehydrated skin in mind, especially skin that prefers light, fragrance-free textures. Individual tolerability varies, so we recommend testing it on a small area before first use.
What is the difference between HEVEBLUE and Isntree Gim PDRN?
Both serums contain PDRN, but they play different roles. HEVEBLUE Salmon Caring Centella Ampoule is built on centella and makes most sense for sensitive skin that flushes easily. Isntree Gim PDRN Hydro Bouncy Ampoule is built on hyaluronic acid and suits skin that feels tight after cleansing.
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<p style="margin: 0;"><strong style="color: #053356;">HEVEBLUE Salmon Caring Centella Ampoule</strong> is a lightweight salmon PDRN serum with centella for sensitive, irritated skin prone to redness. Its main ingredient is centella leaf water, paired with salmon PDRN and hyaluronic acid. Fragrance-free; use morning and evening after toner.</p>
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